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$69 lowest all-in per month, across 432 sellers

Read September 2026

Direct Meds review

Priced per day, sold per quarter

Everything is quoted as a daily figure on an eighty-four or ninety-day supply, and one of those daily figures is wrong on the seller's own page.

What Direct Meds charges, and what it bills

One row per molecule and delivery route. Where the two figures differ, the struck number is what Direct Meds leads with and the figure under it is what a buyer cannot get below. Both are published by the seller; neither is a walked checkout.

ProductPer month6 months
Semaglutide, tabletRead August 2026The seller does not state what happens as the dose rises.$249$1,494
Semaglutide, injectionRead August 2026The seller does not state what happens as the dose rises.$297$1,782
Tirzepatide, tabletRead August 2026The seller does not state what happens as the dose rises.$299$1,794
Tirzepatide, injectionRead August 2026The seller does not state what happens as the dose rises.$399$2,394

The 6-month column is the billed monthly figure multiplied by 6. It is arithmetic on published prices, not a forecast of a bill: a real six months also carries dose changes, labs and shipping, and those are covered below where Direct Meds states them.

The bottom line

Direct Meds prices compounded semaglutide at $297 and compounded tirzepatide at $399, read August 2026, both quoted as 'as low as' and both sold on multi-month supplies rather than by the month. Its public tirzepatide page advertises '$12.87 per day' in one place and '$9.58 per day' in another; the second repeats the semaglutide arithmetic and does not match the tirzepatide price.

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What the figure does not cover

Fees, terms and cancellation at Direct Meds

Prepay
The injections are sold as an eighty-four-day three-pack billed monthly and the orals on a ninety-day supply, read August 2026. What happens to a partly used term if treatment stops is not stated.

Pricing transparency

How Direct Meds publishes its prices

Six months at the $297 semaglutide figure is $1,782, which is arithmetic on a supply sold by the quarter rather than a rate anyone is billed monthly. The oral is quoted at $249, and the portal notes some dosages price as low as $237 on a ninety-day supply. That makes the advertised figure a ceiling on that line rather than a floor, which is an unusual direction. Tirzepatide is $399 injected and $299 oral, on the same multi-month basis. The daily figures are where care is needed: $12.87 a day is consistent with $399, and the '$9.58 per day' also shown for tirzepatide is the semaglutide number appearing on the wrong page.

At a glance

Category
GLP-1 telehealth sellers
Molecule
Semaglutide · Tirzepatide
Form
Injection · Oral
From
$297/mo · injection
From
$249/mo · oral
Prescription
Required
Compounded
Yes — not FDA-approved
Availability
Not published by the provider

The seller

What Direct Meds is

Direct Meds sells compounded semaglutide and compounded tirzepatide, injected and oral, through a portal, with four lines carrying a figure. The injections are supplied as an eighty-four-day three-pack billed monthly, and the orals on a ninety-day supply.

How it works

The purchasing unit is the thing to get straight before comparing anything. An eighty-four-day three-pack billed monthly is not the same commitment as a monthly subscription a buyer can stop, and a ninety-day supply is a quarter bought at once. The daily framing makes the numbers look small, which is presumably why sellers use it, and it obscures how much is owed at the point of purchase.

Branded or compounded

All four lines are compounded, so none is FDA-approved and none is reviewed by the agency before dispensing. Direct Meds does not name the pharmacy that prepares them.

Where the money holds, and where it moves

Predictable

  • Four lines carry published figures
  • Some oral dosages price below the headline
  • Supply length stated on each line

Moves, or is not stated

  • A daily figure on the tirzepatide page is wrong
  • Sold by the quarter, quoted by the day
  • Every figure is hedged 'as low as'
  • No state coverage list is recorded

Who this is worth it for

A buyer comfortable buying a quarter at a time who will check the arithmetic themselves.

Who should price elsewhere

A buyer comparing monthly rates, since nothing here is sold by the month.

Priced against

Sellers to price beside Direct Meds

  • MadeMed

    Buyers ready to commit six months, which is what the advertised figure assumes

    See MadeMed
  • GobyMeds

    Buyers who can pay twelve weeks at once and want the extras inside one number

    See GobyMeds
  • June Health

    Buyers who want the escalation priced before enrolling rather than found in month three

    See June Health
Price every seller on the price desk side by side →

More GLP-1 telehealth sellers priced end to end: Welling HealthWholesome ClinicZera HealthPepton HealthBreeze MedsCare Bare Rx

Sponsored alternative

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Buyers pricing an oral without starting an intake

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Who priced this, and how

CM
Carla Medina

Access reporter · Figures last read September 2026

Every figure above is what Direct Meds publishes on its own pages, read in the month stated beside it, with any charge a buyer cannot decline added back before anything ranks. The rules a price has to meet before it appears here are set out in the methodology. A partnership sets display order on the surfaces that say so and never moves a score — how this site makes money.

Frequently asked

Which daily figure is right for tirzepatide?
$12.87 is the one consistent with the $399 price, while the '$9.58 per day' also shown on the public tirzepatide page matches the semaglutide arithmetic instead.
Am I buying a month?
No. The injections come as an eighty-four-day three-pack and the orals on a ninety-day supply, read August 2026.
Why is the oral sometimes cheaper than advertised?
The portal notes some dosages price as low as $237 against a $249 headline, which makes the advertised figure a ceiling on that line rather than a floor — the opposite of the usual pattern.
Is Direct Meds expensive compared with other GLP-1 telehealth sellers providers?
Direct Meds publishes a starting figure of $249/mo. Across the 106 GLP-1 telehealth sellers providers we review that publish a single monthly figure, those run $76 to $299 with a median of $179, which puts Direct Meds above the median. The other 4 GLP-1 telehealth sellers providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.
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